I would say No otherwise a user can delete a previous entry or just enter a space
I'm thinking not possible re spaces but would be ok with being proved wrong. Every time I've entered one or more leading or trailing spaces in a field while testing they are always stripped out. Seems that spaces can only be between other characters. The only way I've been able to get a zls into a field is with an update query. If I enter a space to remove a value or delete data from a field and set query criteria to "" I get nothing but the new record row. If I specify Is Null then I can get the record with the deleted value.
The more we hear silence, the more we begin to think about our value in this universe.
Paraphrase of Professor Brian Cox.