My first recommendation would be to make the location of this file a Trusted Location because it seems that it is not. That suggests you copied this db from somewhere and installed it in a non trusted location. You got to where you are now because you've bypassed startup code and code may not run in non trusted locations. If any of that is true wtr having copied the file, then there might be code that detects you have opened a copy and it's causing Access to close. We could only detect that by examining the db should you care to post a compacted and zipped copy of your db here. You'd have to include both front and back ends if the db is split.
Sometimes right clicking on the file in Windows Explorer and selecting Properties and choosing "Unblock" is necessary for files that were downloaded from somewhere.
The more we hear silence, the more we begin to think about our value in this universe.
Paraphrase of Professor Brian Cox.