Yes, more info on why the interaction with Excel. If it's for charting, then I agree because IMHO, Access charting stinks. Making so many tables doesn't sound right - especially over and over. Let's see a pic of your table relationships if you set them. Will tell a lot about your design. Read your post at least 2x and wonder if you have the requisite table structure. Even if you do, there shouldn't be a need for make table queries beyond first use i.e. for fast table design. After that, append and delete, not recreate. That's a recipe for bloat at best, and corruption at worst. Might even be that you should be linking Excel back to Access for charting. If not charts, the maybe even Access reports are good enough. Based on your limited info, I can envision a report as being able to present the info you seem to need to assemble.
The more we hear silence, the more we begin to think about our value in this universe.
Paraphrase of Professor Brian Cox.