OK, that was not simple. Well, actually, it is simple. I just don't know where to find good documentation. Anyway, you may need more functionality than just creating the PDF. The following is not going to let you add comments, play around with layers, etc. There are other references that can be made to take advantages of additional libraries. I had to add PDFMaker API 1.0 Type Library
Also, I stumbled across something about acrobat no longer supporting 3D edits directly and you need a third party add in. Anyway, this worked for me. I used Illustrator to create a simple DWG and all the layers were in the PDF when all was said and done.
Code:
'Reference PDFMaker API 1.0 Type Library
Dim strGetFile As String
Dim strMakeFile As String
strGetFile = "\\ServerName\Folder\Sample.dwg"
strMakeFile = \\ServerName\Folder\Result.pdf
Dim objPDFMaker As New PDFMAKERAPILib.PDFMakerApp
Dim lngResult As Long
lngResult = objPDFMaker.CreatePDF(strGetFile, strMakeFile)
'Returns 0 if good
'Returns -1 if bad