I mocked up this as a skeleton form based on the tables:
People
PersonId |
PersonName |
OtherPersonInfo |
1 |
Jim |
|
2 |
John |
|
3 |
Sam |
|
4 |
Mary |
|
5 |
Sue |
|
6 |
Jarhu |
|
7 |
Cyan |
|
Package table

Form and subform

There is no detail, and I don't know your requirements.
In this form/subform the Sender is on the Form, the Receiver and Package details are on the subform.
When you select a Sender, that person is removed from the list that values the Receiver combo.
You select the Receiver and populate the Package info(I have minimized Dimension etc), then Click the Button.
This adds a Package record to the Package table. If you stay on the same Mainform record, you can continue to add Package records.
This is the table set up

You use the People table to value the Sender combo.
You also use the People table to value the Receiver combo, but you remove the Sender from the Receiver list.
Here is the SQL involved to populate the Receiver combo..
Code:
SELECT People.PersonId, People.PersonName
FROM People
WHERE (((People.PersonId)<>[Forms]![frmMain]![CboSender]))
ORDER BY People.PersonName;
Here is the code behind the button click event.
Code:
Private Sub cmdCreate_Click()
Dim sql As String
10 On Error GoTo cmdCreate_Click_Error
20 sql = "Insert into Package (pkgTimeStamp,SenderId,ReceiverId,PkgWeight_oz,PkgDimension_inches,PkgComment,OtherInfoForThisPkg) " _
& " Values(#" & Now & "# ," & Me.Parent.cboSender & " ," & Me.cboReceiver & " ,'" & txtWeight _
& "' ,'" & txtDim & "','" & txtNotes & "' ,'" & txtOtherInfo & "')"
30 Debug.Print sql
40 CurrentDb.Execute sql, dbFailOnError
50 On Error GoTo 0
cmdCreate_Click_Exit:
60 Exit Sub
cmdCreate_Click_Error:
70 MsgBox "Error " & Err.Number & " (" & Err.Description & ") in procedure cmdCreate_Click of VBA Document Form_sfrmPackage"
80 GoTo cmdCreate_Click_Exit
End Sub
And a typical Package record looks like:
Code:
Insert into Package (pkgTimeStamp,SenderId,ReceiverId,PkgWeight_oz,PkgDimension_inches,PkgComment,OtherInfoForThisPkg) Values(#07-Mar-18 4:53:22 PM# ,1 ,4 ,'132' ,'12','This is sample note for Mary' ,'This is other info for Mary and bla bla bal…')
Hope it's helpful.