If you don't mind a bit of guessing, did you create trusted location and put the file there on the pc where you installed runtime version? I cannot imagine it's a compatibility issue between 2019 and 2016. Only other thing that comes to mind is if you developed in 32 bit and the runtime pc is 64 bit, but the message would not be about older vs newer versions; it would be specifically about bitness.
The more we hear silence, the more we begin to think about our value in this universe.
Paraphrase of Professor Brian Cox.