Even when normally in your Excel file are only new entries, to be on safe side it is wise to make sure the append query to add only new data.
Possible ways:
1. In excel table, you create an unique ID column (reads ID from ERP system, or calculates an ID based on date and on some row identifier(s)). In Access file, you have a field for this ID too. The append query will have the syntax like
Code:
INSERT INTO (FieldList)
SELECT ... FROM LinkedExcelTable WHERE ExcelID Not In (SELECT ExcelID FROM AccessTable)
2. You have several fields in Excel table, which together give an unique set of values. In Append query, you use Left Join on LinkedExcelTable and AccessTable, and insert rows where fields in linked AccessTable are Null.