You said you wanted to control these numbers. So you have to ensure you have covered all eventualities.
You pick a random number and for every subsequent pick, you must ensure that number has not been used. If it has then you must pick again and recheck and continue until your pick is unique. You would also have to check if all numbers have been used, and, in your case, present a message indicating that fact. Then what do you do if you have exhausted the number of unique numbers.
The point here is that using autonumbers would give you a very long list of unique numbers (not necessarily sequential nor positive). But handled by Access.