Your combo looks like this https://support.office.com/en-us/art...A001233722#BM4
If so, maybe you should rethink their use. They are a crutch that will keep you limping along as you continue to use and develop your db.
I'm getting the drift that things worked before, properly split or not. While I agree you need to understand what a properly split db architecture is like and maybe not having done so has introduced corruption, it's possible you will go through that exercise and find that the problem remains. Perhaps your changes put locks on the data that you expect others to be accessing at the same time. That part is a bit problematic for me because to cause the problem (outside of corruption) you'd either need to have multiple concurrent users trying to access the same record when one of them has accessed it already, or record locking was set to the entire table. You are using forms to edit the data, yes?
The more we hear silence, the more we begin to think about our value in this universe.
Paraphrase of Professor Brian Cox.