Are these combos unbound? I don't think so, but I'm kinda confused. If you requery a bound control, the bound data should still be there since nothing has happened that should have removed it unless -
If it is possible that after editing a parent value you create a condition where a relationship between the parent combo and any children no longer exists, you will definitely notice a loss of combo list values since the cascade no longer works. This shouldn't affect underlying data unless the form is based on a query that is no longer satisfied by the combinations you've created. In that case, the data could still be in the table but not in the form's underlying query - until you move off of that record. Then it is gone.
This may be a case where the form should be opened either for viewing or editing, but not both at the same time because that would allow you to trap for missing values only during an edit rather than requery on every record change. Either that, or don't bind the cascading combos to the records.
The more we hear silence, the more we begin to think about our value in this universe.
Paraphrase of Professor Brian Cox.